For the Treatment of Chronic Adult Periodontitis

ATRIDOX® (doxycycline hyclate) 10% is a major advancement in the treatment of periodontal disease. It is a locally applied antibiotic (LAA) that is placed gently below the gum line into periodontal pockets where bacteria thrive and cause infection.

ATRIDOX® is the only locally applied antibiotic gel that flows deeply into infected pockets.

  • Flows freely and easily to the bottom of the pocket and adapts to root morphology
  • Controlled release of doxycycline for a period of 21 days1
  • Bioabsorbability eliminates need for removal
  • Allows precise placement for targeted therapy
  • Single syringe effectively treats multiple infected pockets/sites

ATRIDOX® is the only LAA that is clinically proven to achieve all three of the following outcomes in treating chronic adult peridontitis.

  • Gain in clinical attachment2
  • Reduction in probing depths2
  • Reduction of bleeding on probing3

Only ATRIDOX® delivers unbeatable economics.

  • One low, fixed treatment cost per patient – no variable costs per site treated
  • Increase patient acceptance – keep patient fees affordable
  • Increase your standard of care – one low-cost syringe treats eight to 14 sites

ATRIDOX® is an easy-to-use gel that is applied with a syringe into the infected tooth pocket. ATRIDOX® flows to the bottom of pockets and fills even the smallest spaces between teeth and gums. After ATRIDOX® is applied, it hardens upon contact with oral fluids (saliva) to a wax-like substance, and the antibiotic is slowly released into the surrounding infected tooth pocket.

ATRIDOX® Product Insert:
Click here to download the U.S. Version  | Click here to download the Canadian Version

In clinical studies, ATRIDOX® was generally well-tolerated. Side effects were similar to those of placebo. The most common side effects were: headache, common cold, gum discomfort, pain or soreness, toothache and tooth sensitivity. ATRIDOX® should not be used by patients who are hypersensitive to doxycycline or any other drugs in the tetracycline class. The use of drugs in the tetracycline class during tooth development may cause permanent discoloration of the teeth. Tetracycline drugs, therefore, should not be used in pregnant women, unless other drugs are not likely to be effective or are contraindicated.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.