How to Use
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ATRIDOX® Package Contents
- 1 syringe with liquid polymer
- 1 syringe with doxycycline hyclate powder
- 1 sterile blunt cannula
Important
- When removing caps, hold syringes with the nozzles upright to avoid spilling before coupling.
Preparation: Step 1
- Twist and lock syringe A containing liquid polymer with syringe B containing doxycycline powder.
- Inject contents of syringe A into syringe B and then push contents back into syringe A. Mix syringes back and forth 100 times (about 1 ½ minutes). The contents must be in syringe A (indicated by red stripe) when finished.

Preparation: Step 2
- Hold the coupled syringes vertically with syringe A at bottom. Pull back on syringe A plunger and allow contents to flow down the barrel for several seconds.

- Uncouple the two syringes and attach blunt cannula to syringe A.

Administration: Step 1
- Attach blunt cannula as directed.
- After attaching blunt cannula as directed, bend cannula to resemble a periodontal probe.

Administration: Step 2
- Keep cannula tip near pocket base.
- Fill the majority of the pocket with ATRIDOX® while withdrawing the cannula tip from the pocket.
- Withdraw cannula tip from pocket.
- To separate ATRIDOX® from cannula, turn tip toward tooth, press tip against tooth surface and pinch string of formulation against tooth to break off.
- For a clean separation of the cannula from ATRIDOX® in the pocket, consider using a moistened dental hand instrument to ensure proper placement.

Administration: Step 3
- If necessary, add more ATRIDOX® and pack into pocket until pocket is full.
- You are now ready to move to the next pocket.
- It is not necessary to remove ATRIDOX® from the pocket. It will absorb completely.