Download Summaries of Oral Cancer Clinical Studies
ViziLite® TBlue® is a clinically proven screening system that has been helping oral healthcare professionals identify and mark lesions for more than a decade. This system uses a chemiluminescent light source and a patented, GMP manufactured toluidine blue dye called TBlue. TBlue provides the deep blue staining that allows ViziLite TBlue identified lesions to be seen clearly under normal light.
ViziLite and ViziLite TBlue have had numerous clinical studies published supporting its ability to help oral healthcare professionals identify, evaluate, monitor and mark abnormal oral lesions suspicious for pathology including precancerous and cancerous cells that may be difficult to see during a regular visual exam.
Mojsa I, Zaleska M, Stypulkowska J, et al. Value of the ViziLite Plus System as a Diagnostic Aid in the Early Detection of Oral Cancer/Premalignant Epithelial Lesions. J Craniofacial Surg. 2012;23(2):e162-164.
Patton LL, Epstein JB, and Kerr AR. Adjunctive Techniques for Oral Cancer Examination and Lesion Diagnosis: A Systematic Review of the Literature. J Am Dent Assoc. 2008;139:896-905.
Epstein JB, Silverman S Jr, Epstein JD, et al. Analysis of oral lesion biopsies identified and evaluated by visual examination, chemiluminescence and toluidine blue. Oral Oncol. 2008;44(6):615.
Kerr AR, Sirois DA, Epstein JB. Clinical evaluation of chemiluminescent lighting: an adjunct for oral mucosal examinations. New York University College of Dentistry. J Clin Dent. 2006;17(3):59-63.
Epstein JB, Gorsky M, Lonky S, et al. The efficacy of oral lumenoscopy (ViziLite) in visualizing oral mucosal lesions. College of Dentistry and Illinois Cancer Center. Spec Care Dentist. 2006;26(4):171-4.
Ram S, Siar CH. Chemiluminescence as a diagnostic aid in the detection of oral cancer and potentially malignant epithelial lesions. Int J Oral Maxillofac Surg. 2005;34(5):521-7.
Zhang L, Williams M, Poh CF, et al. Toluidine blue staining identifies high-risk primary oral premalignant lesions with poor outcome. University of British Columbia. Cancer Res. 2005;65(17):8017-21.
Huber MA, Bsoul SA, Terezhalmy GT. Acetic acid wash and chemiluminescent illumination as an adjunct to conventional oral soft tissue examination for the detection of dysplasia: a pilot study. University of Texas Health Science Center of San Antonio. Quintessence Int. 2004;35(5):378-84.